Penoxal is a natural dietary supplement which positively influences the immune system. No.
History of the active substance
1972 Discovery of a microorganism Penicillium oxalicum var. Armeniaca
1983 Patenting the microorganism in the USSR
1989 Research and breeding of the microorganism and new strain cultivation
1996 Identification of Biocol (Public Health Office in Prague)
Expert opinion on the active substance in the form of a dietary supplement (NIPH) and launch of the first s
ales
Introducing the product Biocol under the same trade name
1998 Patenting the microorganism in over 130 countries worldwide
Toxicology studies (Research Institute for Pharmacy and Biochemistry Prague, RNDr. Jiri Marhan)
2001 Research and launch of the biotechnological manufacture in Unichov
2003 First studies to testanticancer effects of the active substance (RCD s.r.o, RNDr. Pavla Pouchkova, CSc.)
2005 Second study to testanticancer effects of the active substance on human carcinoma (RCDs.r.o., RNDr. Pavla Pouchkova, CSc.) Determination of the active substance bioactive properties (The Czech Academy of Sciences, Department of Immunology and Photobiology, MUDr. Petr Shima
Approval of the dietary supplement Biocol by the Ministry of Health, Ref. OVZ-350.1.8.0526664/2
2007 Introducing Biocol under a brand name of Gesavit® – 10mg and 50mg with beta-glucan,to the Czech market
2008 Introducing Biocol under a brand name of Penoxal – 50mg with beta-glucan, tothe international markets
2009 Gesavit® clinical studies at University Hospital in Pilsen (Department of Gynaecology and Obstetrics, Doc. MUDr. Zdenek Rokyta, CSc.)
2010 Penoxal clinical studies in 115 patients at the National Centre of Oncology in Yerevan
2011 Gesavit® clinical studies at the Department of Gynaecology and Obstetrics in Prerov Hospital
Gesavit® clinical studies at the Oncology Department in Vsetín Hospital
2015 Marketing strategy planning for the Czech Republic and abroad
Rebranding the Biocol containing products to Penoxal
Purchase of the Gesavit® trademark and end of sales of the products under this name
Launching sales of Penoxal products
