Sugarlipsporebar

Subject: Something SWEET is coming to Catch-22! 🍋✨
​Hello Beautiful Clients ,
​Big things are happening at Sugar Lips Pore Bar!

We are officially expanding our wellness offerings at Catch-22 Treatment Spa here in San Carlos, and I can’t wait for you to taste what’s new.

​I am proud to introduce my handcrafted C*D+

Full-Spectrum Lemonade Shots.

​These aren't your average drinks. Each shot is infused with 100mg of Full-Spectrum C*D and powered by MCT oil for maximum absorption.

Whether you are looking to deep-freeze your anxiety, reduce inflammation, or just find your "mellow" after a massage, these shots are the perfect addition to your treatment.

​Why you’ll love them:

​High Potency: 100mg of Full-Spectrum C*D for a deep, therapeutic effect.

​Clean Energy: Made with premium MCT oil for a fast-acting boost.

​Fresh Flavor: Homemade lemonade—the perfect San Carlos refresher!

​Next time you’re in for a facial or a massage, ask for a "Sugar Lips Shot" to take your relaxation to the

next level.
​Stay sweet,
​Suzanna Carmela
Sugar Lips Pore Bar @ Catch-22 Treatment Spa

# Sugar Lips Pore Bar Products
*Organic Sugar Scrubs*
Indulge in our luxurious, organic sugar scrubs, carefully crafted to exfoliate and nourish your skin. Our sugar scrubs are made with:

- Organic sugar
- Natural oils (Grape seed, Avacado, olive, and jojoba).
- Essential oils for a refreshing scent

*Natural, Artisanal, Handmade Soaps*
Our handmade soaps are crafted with love and care, using only the finest natural ingredients:

- Natural oils (avacado olive, coconut, and palm)
- Essential oils for a refreshing scent
- Herbs and botanicals for added nourishment

*Bath Balms*
Unwind and relax with our nourishing bath balms, infused with:

- Natural oils (coconut, olive, and jojoba)
- Essential oils for a calming scent
- Herbs and botanicals for added relaxation

*C*D Products*
Experience the benefits of C*D with our carefully crafted products:

*Sleep Oil and Salve*
Promote relaxation and improve sleep quality with our C*D sleep oil and salve.

*Topical Pain and Inflammation Relief*
Find relief from pain and inflammation with our C*D topical cream.

*Sleep and Pain-Relieving Chocolates*
Indulge in our delicious, C*D-infused chocolates, carefully crafted to promote relaxation and relief.

*Relaxation Brownies*
Treat yourself to our decadent, C*D-infused brownies, perfect for unwinding and relaxing.

Experience the natural goodness of Sugar Lips Pore Bar products!

https://www.facebook.com/100057184790618/posts/1040968957819254/.

All this time Cancer has been fought with the wrong medications...
All this time ... It's a fu***ng parasite
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235938/

Drug repurposing is a feasible strategy in developing novel medications. Regarding the cancer field, scientists are continuously making efforts to redirect conventional drugs into cancer treatment. This approach aims at exploring new applications in the existing agents. Antiparasitic medications, including artemisinin derivatives (ARTs), quinine-related compounds, niclosamide, ivermectin, albendazole derivatives, nitazoxanide and pyrimethamine, have been deeply investigated and widely applied in treating various parasitic diseases for a long time. Generally, their pharmacokinetic and pharmacodynamic properties are well understood, while the side effects are roughly acceptable. Scientists noticed that some of these agents have anticancer potentials and explored the underlying mechanisms to achieve drug repurposing. Recent studies show that these agents inhibit cancer progression via multiple interesting ways, inducing ferroptosis induction, autophagy regulation, mitochondrial disturbance, immunoregulation, and metabolic disruption. In this review, we summarize the recent advancement in uncovering antiparasitic drugs’ anticancer properties from the perspective of their pharmacological targets. Instead of paying attention to the previously discovered mechanisms, we focus more on newly emerging ones that are worth noticing. While most investigations are focusing on the mechanisms of their antiparasitic effect, more in vivo exploration in clinical trials in the future is necessary. Moreover, we also paid attention to what limits the clinical application of these agents. For some of these agents like ARTs and niclosamide, drug modification, novel delivery system invention, or drug combination are strongly recommended for future exploration.

Keywords: ferroptosis, autophagy, mitochondria, immunoregulation, glycolysis
Go to:
Introduction
Cancer has become one of the biggest threats among all sorts of health concerns.1 According to the Global Burden of Disease Study 2017, cancer-related deaths have increased by 25.4% over the past decade.1 As one of the three main cancer treatments, chemotherapy is the major choice for most types of cancers. While scientists have made progress in reducing the death rates using these agents, existing traditional chemoagents generally have some side effects like nephrotoxicity or myelosuppression, which may limit their application in clinical practice.2 Moreover, some cancers may develop resistance to these agents during the treatment, profoundly reducing the therapeutic effect.3 In this way, it is of great significance to include more effective chemo agents that exhibit antitumor properties in current cancer treatment. Novel medication invention is one of the main ways to develop new drugs. However, such an approach is relatively costly and time-consuming under the current drug designed and development model, based on the fact that it would take more than ten years on average before an invented drug is applied clinically, regardless of the low overall success rate.4 Comparably, drug repurposing is more efficient and money-saving for for the corporations, government and the patients, as such a strategy may help reduce the cost of drug invention, finally reduce the price of the medication. With more available preclinical experiments, clinical trials, and practice, it would take less time and lower cost to apply an approved drug in treating cancer.5

Antiparasitic drugs are a group of chemo agents that act against infections caused by parasites, including artemisinin derivatives (ARTs), quinine-related compounds, niclosamide, ivermectin, albendazole derivatives, nitazoxanide and pyrimethamine (Figure 1). These agents exhibit various modes of effect on parasites. Most of the FDA-approved antiparasitic agents have been applied clinically for a long time, and their pharmacokinetic and pharmacodynamic properties have been explored thoroughly. Moreover, their toxicity on normal human cells and possible adverse effects are well understood and mostly acceptable. In this way, scientists thought of the possibility of redirecting antiparasitic agents for treating cancers.

Progress in Redirecting Antiparasitic Drugs for Cancer Treatment Drug repurposing is a feasible strategy in developing novel medications. Regarding the cancer field, scientists are continuously making efforts to redirect conventional drugs into cancer treatment. This approach aims at exploring new applications in the ...