Learn about essential oils with me.

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01/08/2026

Chronic inflammation forms when an initially protective immune response fails to switch off and becomes a low‑grade, persistent reaction that continually damages tissues instead of repairing them. It usually starts from the same mechanisms as acute inflammation (vasodilation, increased permeability, leukocyte recruitment) but then shifts into a long‑term state dominated by macrophages, lymphocytes, and ongoing cytokine production.[ncbi.nlm.nih +2]
Main triggers
• Persistent infection: Some microbes (for example, Mycobacterium tuberculosis, certain fungi and parasites) resist clearance, so the immune system keeps responding indefinitely.[ncbi.nlm.nih]
• Non‑degradable irritants: Long‑term exposure to particles or chemicals the body cannot break down (such as silica dust or some industrial toxins) leads to continuous activation of immune cells.[ncbi.nlm.nih]
• Autoimmunity: In diseases like rheumatoid arthritis or systemic lupus erythematosus, the immune system mistakes self structures for foreign, so normal tissues are attacked chronically.[sciencedirect +1]
• Metabolic and lifestyle factors: Obesity, insulin resistance, unhealthy diet, smoking, and physical inactivity keep the immune system in a mild “attack mode,” contributing to chronic systemic inflammation.[osu +2]
Cellular shift from acute to chronic
• Early phase: Neutrophils dominate and release proteases, reactive oxygen species, and cytokines to kill pathogens in the acute phase.[ncbi.nlm.nih]
• Transition: If the trigger persists, monocytes migrate into tissue and differentiate into macrophages, while lymphocytes (T and B cells) accumulate.[teachmesurgery +1]
• Chronic phase: Macrophages and lymphocytes become the main effectors, secreting IL‑1, IL‑6, TNF‑α and growth factors that sustain leukocyte recruitment, promote tissue destruction, and drive fibroblast proliferation and angiogenesis.[teachmesurgery +1]
Granulomas and tissue remodeling
• Granuloma formation: When an inciting agent is hard to eradicate (e.g., TB, some foreign bodies, sarcoidosis), macrophages transform into epithelioid cells and sometimes multinucleated giant cells, forming granulomas surrounded by lymphocytes to “wall off” the stimulus.[teachmesurgery +1]
• Fibrosis and scarring: Chronic cytokine and growth factor signaling stimulates fibroblasts to deposit collagen and extracellular matrix, leading to fibrosis that replaces normal architecture and can impair organ function.[teachmesurgery +1]
Systemic effects
• Spillover of mediators: Continuous production of cytokines such as IL‑1, IL‑6, and TNF‑α can extend beyond the original site, contributing to systemic low‑grade inflammation that affects vasculature, metabolism, and the central nervous system.[gaucherdisease +2]
• Link to chronic disease: This persistent inflammatory milieu is associated with higher risk of atherosclerosis, type 2 diabetes, neurodegenerative changes, and other chronic conditions where ongoing immune activation and tissue injury coexist.[clevelandclinic +2]

02/28/2025

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Photos from Learn about essential oils with me.'s post 01/29/2025

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12/31/2024

* Tulsi�Relaxes and Calms your Mind Help Normalize Blood Pressure, Lipids and Glucose
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* Frankincense�Fortifies Your Immune System Supports Healthy Inflammatory Response
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* Turmeric�Supports A Healthy Inflammatory Response
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* Myrrh�Antioxidant to Fight Free Radicals
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* Cinnamon�Supports A Healthy Inflammatory Response Immunity-boosting
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* Anise�Enriches Your Blood To Increase Your Energy
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* Hyssop�Supports Healthy Circulation
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* Milk Thistle�Support Your Liver and the Body’s Detoxification Pathway

11/05/2024

It takes some work, but there is a solution.

11/04/2024

A simple health protocol can do a powerful job.

09/04/2024

Spotted more mosquitoes? Try this oils combo😊

Healing Secrets: The Wisdom of Your Microbiome with Dr. Zach Bush 08/25/2024

https://youtu.be/KWVxOMfUKLU?si=VXfeEmEwDwV4NqsY

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Photos from Learn about essential oils with me.'s post 07/10/2024
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