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I N M Y O P I N I O N
board-certified procedural medicine and aesthetic dermatology in Miami
by Leslie Rohaidy PA AAOPM
📸 work x IMO lifestyle
09/24/2026
If you’ve been thinking about skin tightening procedures/ surgeries, consider trying / trialing lower face treatment with neurotoxin.
This is what I tell patients — try tox first and you’ll have your answer in 2 weeks to see if your happy enough and can hold off on more invasive expensive procedures with a long list of potential complications, scarring, and/or nerve injury.
Don’t believe me? 🫖 ⬇️⬇️⬇️THE BEST RECENT PUBLISHED EVIDENCE DEMONSTRATES NEUROTOXINS WORK!!!!
1. 2025, Journal of the American Academy of Dermatology — Phase III randomized, double-blind, placebo-controlled trial. Adults with moderate-to-severe platysma prominence received 26-36 U onabotulinumtoxinA injected superficially into the platysma. At Day 14, treatment produced highly significant improvement in platysma prominence versus placebo and significantly reduced patient-reported bother with jawline appearance and vertical neck bands.
2. 2025, Aesthetic Surgery Journal — Phase Ill randomized placebo-controlled trial, Level I evidence. Treatment specifically included the upper platysma along the mandibular border. Investigators found significant improvement in platysma prominence, neck bands, and jawline definition, sustained above placebo through 120 days.
3. 2025, Journal of Plastic, Reconstructive & Aesthetic Surgery — systematic review/meta-analysis of randomized trials. This review pooled RCTs comparing onabotulinumtoxinA with placebo and concluded that tox significantly improves moderate-to-severe platysma prominence with favorable aesthetic outcomes. This is probably the strongest “umbrella” citation for the treatment concept.
4. A second 2026 systematic review/meta-analysis in Journal of Cosmetic Dermatology likewise found onabotulinumtoxinA effective and well tolerated for platysma prominence across randomized trials.
PEER REVIEWED EVIDENCED BASED PUBLISHED REFERENCES 👇🏽
1. PMID: 39442886
2. PMID: 39475141
3. PMID: 41197348
4. PMID: 41612547
PRICING • IMOGlow.com
BOOK • IMOGlow.com/Book
QUESTIONS • mailto:[email protected]
PHONE • 305-204-2184
HOURS • Mon - Sat • 10:00am-4:00pm
THOUSANDS OF NATURAL B/A •
GLP-1 receptor agonists (semaglutide, tirzepatide) meaningfully influence dermatologic conditions through improved insulin sensitivity and anti-inflammatory pathways. Clinical improvements have been reported in hidradenitis suppurativa, psoriasis, and alopecia associated with insulin resistance.¹ Importantly, GLP-1 benefits extend beyond weight reduction. A major 2025 Lancet analysis demonstrated that semaglutide’s cardioprotective effects were independent of baseline adiposity and independent of weight loss, indicating additional metabolic mechanisms at play.²
Growing evidence also suggests GLP-1 therapies may reduce cancer incidence and influence tumor biology through immune modulation, reduced circulating insulin, and other pathways unrelated solely to obesity.²³ Preclinical and clinical work demonstrates anticancer activity even in the absence of obesity, and upcoming trials are evaluating GLP-1 therapies alongside standard oncologic treatments.³
Citations
1. Betancourt Ponce M, et al. How do glycemic control medications impact skin conditions? Cutis. 2025;115(1):7–13.
2. The cardioprotective effects of semaglutide were independent of baseline adiposity and weight loss… The Lancet. 2025;606(10556).
3. GLP-1 receptor agonists and cancer: current clinical evidence and translational opportunities for preclinical research. J Clin Invest. 2025;135(21):e194743.
PRICING · IMOGlow.com
BOOK · IMOGlow.com/Book
QUESTIONS · [email protected]
PHONE · 305-204-2184
HOURS · Mon – Sat · 10:00am–4:00pm
THOUSANDS OF NATURAL B/A ·
fire side chat about NAD+, MTHFR ‘mutations’, and vitamin B and B complex.
PRICING • IMOGlow.com
BOOK • IMOGlow.com/Book
QUESTIONS • [email protected]
PHONE • 305-204-2184
HOURS • Mon - Sat •10:00am-4:00pm
THOUSANDS OF NATURAL B/A • Leslie Rohaidy PA AAOPM Fellow
09/04/2026
zaddyyyy
WATCH THIS IS YOU WANT A TIGHTER JAWLINE (MAN OR WOMAN).
If you’ve been thinking about skin tightening procedures/surgeries, consider trying / trialing lower face treatment with neurotoxin.
This is what I tell patients you’ll have your answer in 2 weeks to see if your happy enough and can hold off on invasive expensive procedures with a long list of potential complications, scarring, and/or nerve injury.
THE BEST RECENT PUBLISHED EVIDENCE DEMONSTRATES NEUROTOXINS WORK!!!!
1. 2025, Journal of the American Academy of Dermatology — Phase III randomized, double-blind, placebo-controlled trial. Adults with moderate-to-severe platysma prominence received 26–36 U onabotulinumtoxinA injected superficially into the platysma. At Day 14, treatment produced highly significant improvement in platysma prominence versus placebo and significantly reduced patient-reported bother with jawline appearance and vertical neck bands.
2. 2025, Aesthetic Surgery Journal — Phase III randomized placebo-controlled trial, Level I evidence. Treatment specifically included the upper platysma along the mandibular border. Investigators found significant improvement in platysma prominence, neck bands, and jawline definition, sustained above placebo through 120 days.
3. 2025, Journal of Plastic, Reconstructive & Aesthetic Surgery — systematic review/meta-analysis of randomized trials. This review pooled RCTs comparing onabotulinumtoxinA with placebo and concluded that toxin significantly improves moderate-to-severe platysma prominence with favorable aesthetic outcomes. This is probably the strongest “umbrella” citation for the treatment concept.
4. A second 2026 systematic review/meta-analysis in Journal of Cosmetic Dermatology likewise found onabotulinumtoxinA effective and well tolerated for platysma prominence across randomized trials.
PEER REVIEWED EVIDENCED BASED PUBLISHED REFERENCES 👇🏽
1. PMID: 39442886
2. PMID: 39475141
3. PMID: 41197348
4. PMID: 41612547
PRICING • IMOGlow.com
BOOK • IMOGlow.com/Book
QUESTIONS • [email protected]
PHONE • 305-204-2184
HOURS • Mon - Sat •10:00am-4:00pm
THOUSANDS OF NATURAL B/A •
08/26/2026
‼️ AUDIO ON ‼️
Raise your hand if you have ever messed up a smile or made a lower mouth crooked from less than ideal placement of tox in the lower face?!?
If you are doing chin filler and NOT relaxing the muscle as well you may not be getting an optimal result. In my office they go hand in hand. Sometimes a patient can FORGO using filler entirely when the chin muscle (mentalis muscle) is appropriately relaxed.
As someone who’s been in practice for approximately 9 years and delivered millions of injections, treatments, to thousands of patients - THIS IS MY HACK!
This video also demonstrates the importance of an in-person consultation.
For my providers, you must master the proper injection depth and distance to avoid complications and delivery the best result.
THERE IS NO SUBSTITUTION FOR EXPERIENCE - DO NOT LEARN HOW TO INJECT ON SOCIAL MEDIA
Treat cost: $275
Anesthesia: not used / not necessary
Time: 5 minutes (but years to master!)
Additional treatment: lips were also done and the chin tox has not kicked in yet in any of the videos
QUESTIONS BELOW 👇🏽
PRICING • IMOGlow.com
BOOK • IMOGlow.com/Book
QUESTIONS • [email protected]
PHONE • 305-204-2184
HOURS • Mon - Sat •10:00am-4:00pm
THOUSANDS OF NATURAL B/A • Leslie Rohaidy PA AAOPM Fellow
Not all injectables are created equal ✨
Overfilled jawlines and overly lifted brows can be signs of imbalanced treatment. We believe in full-face harmony — not frozen, overdone results 🤍
PRICING • IMOGlow.com
BOOK • IMOGlow.com/Book
QUESTIONS • [email protected]
PHONE • 305-204-2184
HOURS • Mon - Sat •10:00am-4:00pm
THOUSANDS OF NATURAL B/A •
byeeeeeeee
La que obra bien, termina bien. 🧿
Porque quien siembra bien, cosecha bien. 🌱
En el final, todo cae por su propio peso. ⚖️
PRICING • IMOGlow.com
BOOK • IMOGlow.com/Book
QUESTIONS • [email protected]
PHONE • 305-204-2184
HOURS • Mon - Sat •10:00am-4:00pm
THOUSANDS OF NATURAL B/A • Leslie Rohaidy PA AAOPM Fellow
deep thoughts while I make lunch
References 👇🏽
1. Yu X, Xu J, Cao J, et al. Effect of Nicotinamide Adenine Dinucleotide on Heart Failure Caused by Ischemic Cardiomyopathy: A Randomized, Placebo-Controlled Trial. American Journal of Cardiovascular Drugs. 2026;26(1):97–106.
DOI: 10.1007/s40256-025-00764-7.
Human RCT of direct NAD⁺ administration in 180 patients with ischemic cardiomyopathy/heart failure.
PubMed
2. Gasparrini M, Sorci L, Raffaelli N. Enzymology of extracellular NAD metabolism. Cellular and Molecular Life Sciences. 2021;78(7):3317–3331.
DOI: 10.1007/s00018-020-03742-1.
Key mechanistic reference: extracellular NAD⁺ metabolism by ectoenzymes and generation of NAD⁺ precursors including NMN, NR and NAM that can participate in intracellular NAD⁺ regeneration.
PubMed
3. Shi C, Wen Z, Yang Y, Shi L, Liu D. NAD⁺ metabolism and therapeutic strategies in cardiovascular diseases. Atherosclerosis Plus. 2024;57:1–12.
DOI: 10.1016/j.athplu.2024.06.001.
Recent cardiovascular review covering NAD⁺ depletion, NAD⁺ precursors, mitochondrial metabolism, inflammation, vascular disease and therapeutic NAD⁺ augmentation.
PubMed
4. Wang DD, Airhart SE, Zhou B, et al. Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction. JACC: Basic to Translational Science. 2022;7(12):1183–1196.
DOI: 10.1016/j.jacbts.2022.06.012.
Human NR trial demonstrating increased NAD⁺ alongside assessment of mitochondrial respiration and inflammatory signaling in heart failure.
PubMed
5. Katayoshi T, Uehata S, Nakashima N, et al. Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial. Scientific Reports. 2023;13:2786.
DOI: 10.1038/s41598-023-29787-3.
Human NMN RCT examining NAD⁺ metabolism and cardiovascular/arterial-stiffness endpoints.
🧬🧬🧬
PRICING • IMOGlow.com
BOOK • IMOGlow.com/Book
QUESTIONS • [email protected]
PHONE • 305-204-2184
HOURS • Mon - Sat •10:00am-4:00pm
THOUSAND
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